Marta Álvarez Presas has a degree in Biology from the University of Barcelona (UB). She did her doctoral thesis on the phylogeny and phylogeography of terrestrial planarians in the Brazilian Atlantic Forest and Europe.
In 2015, she completed her first postdoc at the UB with a grant from the Generalitat de Catalunya, delving into the use of new generation techniques (NGS). In 2018 she did a stay at the Center for Genomic Regulation of Barcelona (CRG) to improve her skills in bioinformatics. In 2019 she was an associate researcher at the Instituto de Biología Evolutiva (IBE, CSIC) in Barcelona, beginning a study on the origin of Bilateral animals. Between 2019 and 2022 she got a contract with the University of Bristol (United Kingdom), studying the evolution of parasitism using comparative genomics.
In April 2023 she returns to the IBE as a ComFuturo fellow, where she will study, with her project REGULOMICS, the origin of multicellularity through the analysis of gene regulation in different groups of unicellular organisms, relatives of animals.
Extended project summary:
The complexity of animals amazes us, and with good reason. Animals are marvellous in so many ways, behaviourally, morphologically, and genetically. However, how multicellular animals evolved from their single-celled ancestors remains a mystery. In the last decade, we have come a long way in understanding the origins of animals, from identifying the closest unicellular relatives of animals (choanoflagellates, phylastereans, ichthyosporeans, corallochytreans) to studying their biology and sequencing their genomes. Thanks to these efforts, we now know what the unicellular ancestor of animals was like: a more complex creature than expected and already presenting genes (and molecular mechanisms) that in animals are involved in functions related to multicellularity.
What differentiates animals from their single-celled relatives? What specific regulatory features were key for animals to evolve? We now have both the knowledge and the genetic tools necessary to answer these questions. Therefore, REGULOMICS propose the use of these tools to study how genes are regulated, activated and deactivated in cells in the unicellular relatives of animals. It involves understanding the mechanisms that control gene expression, or how information from genes is used to make proteins that perform various functions in cells. The data generated will undoubtedly bring us closer to solving the mystery of animal origins, by unveiling the origin of animal genomic regulation. Furthermore, taking advantage of the numerous available genomes of unicellular relatives of animals, we will study the evolution of regulation and metabolism genes in these groups. The data obtained will also be relevant to many other disciplines, from evolution to genomics, development and cell biology.